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LP44 hydrochloride
CAS No. 824958-12-5
LP44 hydrochloride( —— )
Catalog No. M33879 CAS No. 824958-12-5
LP44 hydrochloride is a selective and potent 5-HT7 agonist (Ki:0.22 nM).LP44 hydrochloride has analgesic effects on formalin-induced orofacial pain in mice and can be used in the study of neuroinflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 50 | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLP44 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionLP44 hydrochloride is a selective and potent 5-HT7 agonist (Ki:0.22 nM).LP44 hydrochloride has analgesic effects on formalin-induced orofacial pain in mice and can be used in the study of neuroinflammation.
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DescriptionLP44 (hydrochloride) is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration.
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In Vitro——
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In VivoLP44 (hydrochloride) (5.1, 10.3, 20.5, 41.0 nmol; i.c.v.) produces dose-dependent hypothermic effect in CBA mice.
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number824958-12-5
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Formula Weight488.13
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Molecular FormulaC27H38ClN3OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (204.86 mM; Ultrasonic )
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SMILESCl.O=C(NC1C=2C=CC=CC2CCC1)CCCCCN3CCN(C=4C=CC=CC4SC)CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Naumenko VS,et al. On the role of brain 5-HT7 receptor in the mechanism of hypothermia: comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor. Neuropharmacology. 2011 Dec;61(8):1360-5.?
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